The study assessed pregnant women’s knowledge and attitude about rhesus incompatibility prevention at Babcock University Teaching Hospital Ilishan-Remo Ogun State. The research design adopted in this study was a non-experimental descriptive survey. The sample size of 140 was derived using Taro Yamane’s formula. Convenience sampling technique was adopted to select the study subjects. Data collection was done by the use of structured questionnaire designed by the researcher. The instrument was validated by experts in the clinical area and Tests and Measurement who ensured the face and content validity. The reliability of the instrument was tested through the use of pilot study on ten (10) respondents from the antenatal clinic of a different setting. It was subjected to Cronbach Alpha co-efficient test and 0.89 was obtained which made the instrument to be reliable. The data collected was subjected to descriptive and inferential statistics. The findings of the result revealed that pregnant women have a fair knowledge of rhesus factor and incompatibility but are not aware of the importance of taking the test and the complications it posed to the health of their babies. It was recommended among others that there is need for consistent education on the knowledge and prevention of rhesus incompatibility among pregnant women. Special attention should be focused on improving respondents’ knowledge by using appropriate educational intervention that addresses the gap in knowledge gap.

Keywords: Knowledge, Rhesus Factor, Rhesus Incompatibility, Prevention, Attitude, Pregnant Women,

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