The study evaluated the outcome of intervention programme on knowledge and skills of standard precautions among nurses in general hospitals in Ogun State, Nigeria. The study adopted pre and post-test one group quasi-experimental design. The sample size for this study was 38 nurses. Multi stage sampling procedure was used to select the sample. A structured questionnaire and observation checklist were used as tools for collecting information from the respondents. Both face and content validity of the instrument were determined by experts of Tests and Measurement with background knowledge in Nursing Science. Cronbach Alpha was used to compute the reliability coefficients. On knowledge of standard precautions, reliability co-efficient of 0.76 was obtained while 0.74 was obtained for skills towards implementation of standard precautions. It was revealed that the pre-intervention knowledge and skills of nurses on standard precautions in intervention group were moderate while post intervention knowledge and skills were high. Intervention programme on standard precautions improves knowledge and skills of standard precautions among nurses as there were differences in pre and post intervention mean knowledge and skills score on standard precautions. It was recommended among others that hospitals should regularly organise in-service training for nurses on standard precautions. Also, an infection control unit should be established to oversee the standard precautions skills of nurses and to ensure the availability of necessary infection control materials.

Keywords: Outcome, Intervention Programme, Knowledge, Skills, Standard Precautions, Nurses,

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