This study examined the utilization and perceived effects of psychoactive substances among selected secondary school students in Ise Orun LGA, Ekiti State, Nigeria. The research focused on three specific objectives: assessing the level of psychoactive substance use, identifying the substances commonly used, and evaluating the perceived effects of such use among senior secondary students. Employing a descriptive research design, data were gathered from a sample of 160 students across five randomly selected schools in Ise Orun LGA. The data collection tool was a structured questionnaire validated through expert review and reliability testing. Analysis of the 150 returned questionnaires revealed significant findings: alcohol, narcotic analgesics, cigarettes, cannabis, and cocaine were commonly used substances among the students. The perceived effects included increased appetite, feelings of happiness and euphoria, engagement in risky behaviors, truancy, hooliganism, and potential mental disorders. Statistical analysis showed a significant relationship between gender and psychoactive substance use, as well as between substance use and academic performance. The study concluded that psychoactive substance use among students poses severe risks to their health and future prospects, influenced by factors like family habits and peer pressure. Recommendations include implementing age restrictions on alcohol and cigarette use, enhancing monitoring and counseling within schools, and conducting regular enlightenment programs on the dangers of psychoactive substance use.

Keywords: Utilisation, Perceived Effect, Psychoactive Substances, Students,

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